专利名称:COMPOSITIONS AND METHODS FOR THE
ANALYSIS AND TREATMENT OF AIDSWASTING SYNDROME AND IMMUNE CELLDYSFUNCTION
发明人:DOMINY, STEPHEN S.申请号:EP07754998申请日:20070405公开号:EP2004841A4公开日:20090902
摘要:The present invention relates to aberrant cell signaling by the HIV type Ienvelope glycoprotein. In particular, the present invention provides compositions andmethods for identification of inhibitors of melanocortin receptor pathway stimulation byHIV-I gpl20 and its degradation products. The inhibitors so identified are contemplatedto be suitable for treating HIV-related cachexia, T cell hyperactivation and centralnervous system disease.
申请人:THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
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