专利名称：HEMATOPOIETIC STEM CELL SPECIFIC
REPORTER MOUSE AND USES THEREOF
发明人：ROSSI, DERRICK J.,GAZIT, ROI申请号：EP13835750申请日：20130906公开号：EP2893017A4公开日：20160525
摘要：Described herein are nucleic acid constructs, hematopoietic stem cell identifieranimals, and methods of using thereof for isolating hematopoietic stem cell populations.Also provided are methods of using the identifier animals and cells isolated from them toscreen for agents that affect the growth, proliferation, potency, expansion, or
maintenance of the stem cells. Such agents can be used for promoting growth of stemcells in vitro or in vivo, and also for inhibiting cancer cells that have been determined toresemble a stem cell.
申请人：CHILDREN'S MEDICAL CENTER CORPORATION
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