Methods for the determination and adjustment of pr

专利名称：Methods for the determination and

adjustment of prolactin daily rhythms

发明人：Albert H. Meier,Anthony H. Cincotta申请号：US07/995292申请日：19921222公开号：US05585347A公开日：19961217

摘要：Disclosed are methods for detecting abnormalities in prolactin daily rhythms.The methods involve comparing a prolactin profile of a vertebrate (including a human)subject being tested that has been compiled over a predetermined period to a

predetermined standard prolactin profile for healthy subjects. The method also involvesdetermining whether the vertebrate subject has an abnormal daily prolactin rhythm byascertaining whether (i) at any point during waking hours the prolactin level of the subjectbeing tested is greater than 1 SEM above the normal prolactin profile of said healthysubjects, and/or (ii) at any point during sleeptime the prolactin level of the subject beingtested is at least 1 SEM lower than the normal prolactin profile of said healthy subjects.Also provided are methods for determining adjustments needed to an abnormalprolactin profile (or daily rhythm) to cause it to conform to the prolactin profile (orrhythm) of a healthy subject, and methods for effecting such adjustments.

申请人：ERGO SCIENCE INCORPORATED,BOARD OF SUPERVISORS OF LOUISIANASTATE UNIVERISITY AND AGRICULTURAL AND MECHANICAL COLLEGE

代理机构：Darby & Darby, P

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