专利名称:T-CELL MEMBRANE PROTEIN发明人:SHERMAN M. WEISSMAN,MIGUEL A.
ALONSO
申请号:AU1574188申请日:19880323公开号:AU1574188A公开日:19881102
摘要:A 16.7 kilodalton membrane protein which is produced in mature, but no early-stage, T cells has been discovered. The protein has four distinct amphipathic domains,each having an amino acid composition which is predictive of an alpha helical structurethat would be stable in a lipid bilayer. Each of these regions is flanked by a relativelypolar domain whose amino acid sequence is predictive of beta pleat peptide regions. Anantibody specific against one of the polar domains can be used to discriminate mature T-cells in a mixed-cell sample.
申请人:YALE UNIVERSITY
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