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T-CELL MEMBRANE PROTEIN

2023-05-26 来源:步旅网
专利内容由知识产权出版社提供

专利名称:T-CELL MEMBRANE PROTEIN发明人:SHERMAN M. WEISSMAN,MIGUEL A.

ALONSO

申请号:AU1574188申请日:19880323公开号:AU1574188A公开日:19881102

摘要:A 16.7 kilodalton membrane protein which is produced in mature, but no early-stage, T cells has been discovered. The protein has four distinct amphipathic domains,each having an amino acid composition which is predictive of an alpha helical structurethat would be stable in a lipid bilayer. Each of these regions is flanked by a relativelypolar domain whose amino acid sequence is predictive of beta pleat peptide regions. Anantibody specific against one of the polar domains can be used to discriminate mature T-cells in a mixed-cell sample.

申请人:YALE UNIVERSITY

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