ANTI-MALARIA VACCINE COMPOSITIONS AND USES THEREOF

专利名称：ANTI-MALARIA VACCINE COMPOSITIONS

AND USES THEREOF

发明人：Stanislas Tomavo,Steven Graham

Ball,Christophe D'Hulst,David Dauvillee

申请号：US12523812申请日：20080123

公开号：US20100199391A1公开日：20100805

摘要：The present invention relates to a polypeptide in which: (i) the N-terminalsequence includes the polypeptide sequence of the GBSSI (Granule Bound StarchSynthase I) or a derivative or fragment thereof, wherein said polypeptide sequence canbind to starch; and (ii) the C-terminal sequence includes a polypeptide sequence codingfor at least one epitope of an antigen from a parasite of the type; the invention alsorelates to a polynucleotide coding for such polypeptide, a vector containing said

polynucleotide, a cell transformed by such vector, a transformed organism including suchtransformed cell, a pharmaceutical composition containing such polypeptide, and the useof such polypeptide in the preparation of a drug for the prophylactic treatment of asubject suffering from a pathology associated with a -type parasite, preferably malaria.

申请人：Stanislas Tomavo,Steven Graham Ball,Christophe D'Hulst,David Dauvillee

地址：Marquette Lez Lille FR,Bourghelles FR,Watterlos FR,Villeneuve D'Ascq FR

国籍：FR,FR,FR,FR

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