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Glycosylated insulin derivatives

2022-03-04 来源:步旅网
专利内容由知识产权出版社提供

专利名称:Glycosylated insulin derivatives发明人:McRea, James C.申请号:EP88120072.9申请日:19831115公开号:EP0312127A2公开日:19890419

摘要:Synthesized p-(succinylamido)-phenyl-α -D-gluco- and mannopyranosides andp-(glutarylamido)-phenyl-α-D-gluco- and mannopyranosides and carboxy homologuesthereof are reacted with insulin to form corresponding glycosylated insulins containingfrom 1 to 3 glycosyl groups per insulin molecule. The novel glycosylated insulins resistaggregation and show significant activity in depressing blood sugar levels.

申请人:UNIVERSITY OF UTAH

地址:Technology Transfer Office 421 Wakara Way, Suite 170 Salt Lake City, Utah84108 US

国籍:US

代理机构:Silverman, Warren

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